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2022 Week 11 MNF Betting: Rondale Moore Receiving Yards and Other Props for Cardinals-49ers

The Arizona Cardinals need a miracle to stay in the playoff hunt in the NFC, and such a journey would need to begin with a victory over the San Francisco 49ers on Monday Night Football.

The 49ers are 10-point favorites in this game and you can check out my prediction in the Tweet below.

Here are three prop bets I like for the contest:

Cardinals WR Rondale Moore over 53.5 receiving yards (-105 at FanDuel)

Moore has found his place within the Arizona offense, averaging eight catches and 85 yards per game over his past three outings. DeAndre Hopkins is the go-to guy in the passing game, but Moore will be the clear-cut second option on Monday with Zach Ertz and Hollywood Brown sidelined.

There was quick chemistry with backup quarterback Colt McCoy last week, as Moore caught nine passes for 94 yards on 13 targets. Moore has zoomed past 55 receiving yards in his past three games and I think he is in line for a heavy workload again in this game.

Moore runs a lot of short routes but has the game-breaking speed to rack up the yardage, and the over is an easy call for me, especially at these odds.

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49ers RB Christian McCaffrey over 35.5 receiving yards (-115 at BetMGM)

This is the second of three meetings between McCaffrey and the Cardinals’ defense. The star running back was on the Panthers in Week 4 and caught nine passes for 81 yards and a touchdown against Arizona.

There are more weapons on his new team but San Francisco still wants to get McCaffrey the ball. He has played two games full-time with the 49ers and has averaged six catches for 47 yards in those contests, reaching 36 yards in both of them.

The Cardinals are ranked No. 30 in the NFL in covering running backs, per Football Outsiders, and rangy linebacker Isaiah Simmons could be playing safety in this game due to the injury to cornerback Byron Murphy.

All signs point toward a strong receiving outing for McCaffrey.

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Cardinals LB Zaven Collins over 6.5 tackles (-105 at DraftKings)

Collins could get some of the assignment against McCaffrey on pass plays, which could help him get tackles there. But he will do most of his work against the ground game.

San Francisco has a fantastic rushing attack and will get to the second level often. That’s where Collins will be, which means the tackle total could be high.

The game script also favors this bet. The 49ers are expected to be winning late in this matchup, which means plenty of rushing attempts.

Collins has reached seven combined tackles or more in six of 10 games this year and I believe it will continue against the 49ers.

This week’s prop bets record: 1-4
Overall: 59-51

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